高強度聚焦超聲在腫瘤治療中的應用_《中國普外基礎與臨床雜志》

作者：

四川大學華西醫院肝膽胰研究室（成都610041）;

關鍵詞：

高強度聚焦超聲腫瘤治療

視頻：

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摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

目的探討高強度聚焦超聲在腫瘤治療中的意義及其局限性。方法用文獻綜述的方法對高強度聚焦超聲在腫瘤治療中的應用及其局限性進行討論。結果高強度聚焦超聲能將超聲波聚焦于機體深部，在極短的時間內使靶區溫度驟升，直接殺死靶區腫瘤，而對于靶區外組織無損傷。具有并發癥少、全身反應小、可重復治療等優勢。但其應用也受影像學技術、臟器的運動、含氣腔道和骨性組織等因素的影響。結論高強度聚焦超聲是一種非侵入性局部治療腫瘤的方法，有巨大的應用前景。

引用本文： 李志宇,綜述,何生,審校. 高強度聚焦超聲在腫瘤治療中的應用. 中國普外基礎與臨床雜志, 2002, 9(2): 139-141. doi: 復制

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14.	Hynynen K, Chung AH, Colucci V, et al. Potential adverse effects of highintensity focused ultrasound exposure on blood vessels in vivo \[J\]. Ultrasound Med Biol, 1996; 22(2)∶193.
15.	Prat F, Centarti M, Sibille A, et al. Extracorporeal highintensity focused ultrasound for VX2 liver tumors in the rabbit \[J\]. Hepatology, 1995; 21(3)∶832.
16.	伍烽，王芷龍，張吉吉，等. 高強度聚焦超聲治療劑量與抑制H22肝癌生長效應的關系 \[J\]. 中國超聲醫學雜志， 1999； 13（6）∶1.
17.	Chen L, Haar G, Hill CR, et al. Influence of ablated tissue on the formation of highintensity focused ultrasound lesions \[J\]. Ultrasound Med Biol, 1997; 23(6)∶921.
18.	程樹群，周信達，湯釗猷，等. 體外高功率聚焦超聲破壞肝組織的實驗研究 \[J\]. 華人消化雜志， 1998； 6（3）∶198.
19.	Clarke RL, Haar GR. Temperature rise recorded during lesion formation by highintensity focused ultrasound \[J\]. Ultrasound Med Biol, 1997; 23(2)∶299.
20.	MassarMoreno R, Dimianou CA, Saughvi NT. Noninvasive temperature estimation in tissue via ultrasound echoshifts. Part Ⅱ: in vitro study \[J\]. J Acoust Am, 1996; 100(4 pt 1)∶2522.
21.	Bohris C, Schreber WG, Jenne J, et al. Quantitative MR temperature monitoring of highintensity focused ultrasound therapy \[J\]. Magn Reson Imaging, 1999; 17(4)∶ 603.

1. Hill CR, Haar GR. Review article: high intensity focused ultrasoundpotential for cancer treatment \[J\]. Br J Radiol, 1995; 68(816)∶1296.
2. 伍烽，陳文直，白晉，等. 高強度聚焦超聲治療原發性肝癌的初步臨床研究 \[J\]. 中華醫學影像學雜志， 1999； 8（1）∶213.
3. Chapelon JY, Ribault M, Vernier F, et al. Treatment of localized prostate cancer with transrectal high intensity focused ultrasound \[J\]. Eur J Ultrasound, 1999; 9(1)∶314Chaussy CG, Thuroff S. Highintensity focused ultrasound in localized prostate cancer \[J\]. J Endourol, 2000; 14(3)∶293.
4. Gelet A, Chapelon JY, Bouvier R, et al. Local control of prostate cancer by transrectal high intensity focused ultrasound therapy: preliminary results \[J\]. J Urol, 1999; 161(1)∶156.
5. Beerlage HP,Thuroff S,Debruyne FMJ,et al.Transrectal highintensity focused ultrasound using the ablatherm device in the treatment of localized prostate carcinoma \[J\]. Urology, 1999; 54(2)∶273.
6. Sanghvi NT, Foster RS, Bihrle R, et al. Noninvasive surgery of prostate tissue by high intensity focused ultrasound: an updated report \[J\]. Eur J Ultrasound, 1999; 9(1)∶19.
7. Madersbacher S, Schatzl G, Djavan B, et al. Longterm outcome of transrectal highintensity focused ultrasound therapy for benign prostatic hyperplasia \[J\]. Eur Urol, 2000; 37(6)∶687.
8. Uchida T, Muramoto M, Kynnou H, et al. Clinical outcome of highintensity focused ultrasound for treating benign prostatic hyperplasia: preliminary report \[J\]. Urology, 1998; 52(1)∶66.
9. Yang R, Clarence R, Reilly FJ, et al. Effects of highintensity focused ultrasound in the treatment of experimental neuroblastoma \[J\]. J Ped Surg, 1992; 27(2)∶ 246.
10. 賈瑞鵬，周性名，張忠林，等.高強度聚焦超聲對小鼠移植性膀胱腫瘤的殺傷效應及免疫功能的影響 \[J\]. 中華泌尿外科雜志， 1998； 19（6）∶ 270.
11. Barkman CA, Almquist LO, Kirkhorn T, et al. Thermotherapy: feasibility study using a single focused ultrasound transducer \[J\]. Int J Hyperthermia, 1999; 15(1)∶ 63.
12. 程樹群，周信達，湯釗猷，等. 高功率聚焦超聲高溫破壞肝腫瘤的病理學改變 \[J\]. 中華實驗外科雜志， 1996； 13（3）∶135.
13. 阮祥燕，杜永洪，孔繁斌，等. 高強度聚焦超聲定位損傷香豬肝臟組織的病理轉歸研究 \[J\].中華實驗外科雜志，1999； 16（3）∶ 263.
14. Hynynen K, Chung AH, Colucci V, et al. Potential adverse effects of highintensity focused ultrasound exposure on blood vessels in vivo \[J\]. Ultrasound Med Biol, 1996; 22(2)∶193.
15. Prat F, Centarti M, Sibille A, et al. Extracorporeal highintensity focused ultrasound for VX2 liver tumors in the rabbit \[J\]. Hepatology, 1995; 21(3)∶832.
16. 伍烽，王芷龍，張吉吉，等. 高強度聚焦超聲治療劑量與抑制H22肝癌生長效應的關系 \[J\]. 中國超聲醫學雜志， 1999； 13（6）∶1.
17. Chen L, Haar G, Hill CR, et al. Influence of ablated tissue on the formation of highintensity focused ultrasound lesions \[J\]. Ultrasound Med Biol, 1997; 23(6)∶921.
18. 程樹群，周信達，湯釗猷，等. 體外高功率聚焦超聲破壞肝組織的實驗研究 \[J\]. 華人消化雜志， 1998； 6（3）∶198.
19. Clarke RL, Haar GR. Temperature rise recorded during lesion formation by highintensity focused ultrasound \[J\]. Ultrasound Med Biol, 1997; 23(2)∶299.
20. MassarMoreno R, Dimianou CA, Saughvi NT. Noninvasive temperature estimation in tissue via ultrasound echoshifts. Part Ⅱ: in vitro study \[J\]. J Acoust Am, 1996; 100(4 pt 1)∶2522.
21. Bohris C, Schreber WG, Jenne J, et al. Quantitative MR temperature monitoring of highintensity focused ultrasound therapy \[J\]. Magn Reson Imaging, 1999; 17(4)∶ 603.

《中國普外基礎與臨床雜志》

高強度聚焦超聲在腫瘤治療中的應用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

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Content

《中國普外基礎與臨床雜志》

高強度聚焦超聲在腫瘤治療中的應用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料