腫瘤細胞的多藥耐藥性的產生與P糖蛋白(PgP)及谷胱甘肽轉移酶(GST)等的過度表達有密切關系。為進一步了解胃和食管惡性腫瘤細胞的耐藥機理,為化療中克服耐藥,制定合理、高效的化療方案提供依據。
                                 
                               
                                     
                                  
                       
                           引用本文:
                           薛軍,支學軍,屈明,楊東東,薄愛華. 胃癌及食管癌中腫瘤耐藥標志物P-糖蛋白和谷胱甘肽轉移酶表達的研究. 中國普外基礎與臨床雜志, 2002, 9(5): 1-01. doi: 
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				                                                                | 2. | 吳名耀,沈健,吳賢英. P糖蛋白在食管癌中的表達及其臨床意義 [J].臨床及實驗病理學雜志,1997; 13(20)∶192. | 
				                                                        
				                                                            
				                                                                | 3. | Tsuchida S, Sekine Y, Shineha R, et al. Elevation of the placental glutathione Stransferase form (GSTpi) in tumor tissues and the levels in sera of patients with cancer [J].Cancer Res, 1989; 49(18)∶5225. | 
				                                                        
				                                                            
				                                                                | 4. | Hamada S, Kamada M, Furumoto H, et al. Expression of glutathione Stransferasepi in human ovarian cancer as an indictor of resistance to chemotherapy [J].Gynecol Oncol, 1994; 52(3)∶313. | 
				                                                        
				                                                    
				                                                 
				                                             
				                                            
                             
                            
                                
                               		 
		                                
		                                    - 1.  Ramani P, Dewchand H. Expression of mdr1/Pglycoprotein and p110 in neuroblastoma [J]. J Pathol, 1995; 175(1)∶ 13.		                                    
		                                    
- 2.  吳名耀,沈健,吳賢英. P糖蛋白在食管癌中的表達及其臨床意義 [J].臨床及實驗病理學雜志,1997; 13(20)∶192.		                                    
		                                    
- 3.  Tsuchida S, Sekine Y, Shineha R, et al. Elevation of the placental glutathione Stransferase form (GSTpi) in tumor tissues and the levels in sera of patients with cancer [J].Cancer Res, 1989; 49(18)∶5225.		                                    
		                                    
- 4.  Hamada S, Kamada M, Furumoto H, et al. Expression of glutathione Stransferasepi in human ovarian cancer as an indictor of resistance to chemotherapy [J].Gynecol Oncol, 1994; 52(3)∶313.