腸道動力學改變在急性胰腺炎的病程及治療中的意義_《中國普外基礎與臨床雜志》

作者：

陳曉理 ¹ , 馮凱祥 ²

1. 華西醫科大學附屬第一醫院普外科(成都610041)2. 四川省綿陽市中心醫院消化內科;

關鍵詞：

急性胰腺炎腸運動細菌移位內毒素血癥

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通過在蛙皮縮膽囊素(caerulein,Cn)誘導的輕癥胰腺炎時用阿片類止瀉劑(lopemin)抑制腸運動和在脫氧膽酸胰管注射的重癥胰腺炎時用大黃促進腸運動的兩個系列鼠實驗為基礎，探討了腸道運動力學改變對急性胰腺炎的病程和預后的影響。結果顯示：抑制運動將增加胰腺炎的繼發感染和內毒素血癥，反之促進腸運動則減少細菌移位和內毒素血癥，從而降低實驗大鼠的死亡率。提示：腸動力學改變與急性胰腺炎的病程及預后有密切關系，通過促進腸道運動可減少急性胰腺炎的繼發感染和多器官衰竭，從而改善胰腺炎的預后。

引用本文： 陳曉理,馮凱祥. 腸道動力學改變在急性胰腺炎的病程及治療中的意義. 中國普外基礎與臨床雜志, 1999, 6(6): 325-327. doi: 復制

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1. Renner IG, Savage WT, Panbtoja TL, et al. Death due to acute pancreatitis: a retrospective analysis of 405 autopsy cases. Dig Dis, 1985; 30(3)∶1005.
2. Rabeneck L, Feinstein A, Horwitz RL, et al. A new clinical prognostic staging system for acute pancreatitis. Am J Med, 1993; 95(1)∶61.
3. Schmidt J, Warshaw AL. A better model of acute pancreatitis for evaluating therapy. Ann Surg, 1992; 215∶44.
4. Sharahan F. The intestinal immune system. In: Johnson LR ed. Physiology of gastrointestinal tract. 3th ed. New York: Raven Press Ltd, 1994; 1(2)∶643.
5. Scott LD. Influence of influence of interdigestive myoelectric complex on enteric flora in rat. Gastroenterology, 1982; 82(3)∶737.
6. Runkel NSF, Moody FG, Smith GS, et al. The role of the gut in development of sepsis in acute pancreatitis. J Surg Res, 1991; 51(1)∶18.
7. Shikata J, Shida T, Amino K. Experimental study on hemodynamic of small intestine following increased intraluminal pressure. Surg Gynecol Obsttet, 1983; 156(1)∶155.

《中國普外基礎與臨床雜志》

腸道動力學改變在急性胰腺炎的病程及治療中的意義

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《中國普外基礎與臨床雜志》

腸道動力學改變在急性胰腺炎的病程及治療中的意義

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

Content

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