膀胱小細胞癌一例_《華西醫學》

作者：

何建萍 , 劉繼彥 , 易成 , 畢鋒 , 許峰

四川大學華西醫院腹部腫瘤科（成都，610041）;

關鍵詞：

膀胱腫瘤小細胞癌

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【摘要】　目的　總結膀胱小細胞癌的診斷及治療。　方法　 2009年8月1例行根治性膀胱切除、回腸代膀胱術患者經病理學、免疫組織化學檢查確診為膀胱小細胞癌。患者接受EP治療方案治療。　結果　治療4周期后，復查CT未見轉移，無Ⅲ~Ⅳ級毒副反應。　結論　膀胱小細胞癌需依靠病理學及免疫組織化學檢查確診，治療目前參考小細胞肺癌治療方案，以化學療法為主，復習文獻得出有無手術切除并不影響膀胱小細胞癌患者的預后，靶向藥物的治療尚需進一步研究。

引用本文： 何建萍,劉繼彥,易成,畢鋒,許峰. 膀胱小細胞癌一例. 華西醫學, 2011, 26(2): 246-247. doi: 復制

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5.	Abrahams NA, Moran C, Reyes AO, et al. Small cell carcinoma of the bladder: a contemporary clinicopathological study of 51 cases[J]. Histopathology, 2005, 46(1): 57-63.
6.	曹志彬. 膀胱小細胞癌: 一種罕見的膀胱癌[J]. 國際泌尿系統雜志, 2006, 26(1): 25-28.
7.	Bastús R, Caballero JM, González G, et al. Small cell carcinoma of the urinary bladder treated with chemotherapy and radiotherapy: resul tsin five cases[J]. Eur Urol, 1999, 35(4): 323-326.
8.	Grignon DJ, Ro JY, Ayala AG, et al. Small cell car-cinoma of the urinary bladder. A clinicopathologic analysis of 22 cases[J]. Cancer, 1992, 69(2): 527-536.
9.	潘進勇, 王曉維. 膀胱小細胞癌的研究進展[J]. 中華腫瘤防治雜志, 2007, 6(14): 864-865.
10.	Abbas F, Civantos F, Benedetto P, et al. Small cell carcinoma of the bladder and prostate[J]. Urology, 1995, 6(5): 617-630.
11.	Choong NW, Quevedo JF, Kaur JS. Small cell carcinoma of the urinary bladder. The Mayo Clinic experience[J]. Cancer, 2005, 103(6): 1172-1178.
12.	Dreicer R, Manola J, Roth BJ, et al. Phase Ⅱ study of cisplatin and paclitaxel in advanced carcinoma of the urothelium: an Eastern Cooperative Oncology Group Study[J]. J Clin Oncol, 2000, 18(5): 1058-1061.
13.	Bajorin DF, McCafrey JA, Dodd PM, et al. Ifosfamide, paclitaxel, and cisplatin for patients witll advanced transitional cell carcinoma of the urothelial tract: final report of a phase Ⅱ trial evaluating two dosing schedules[J]. Cancer, 2000, 88(7): 1671-1678.
14.	Pan CX, Yang XJ, Lopez-Behran A, et al. c-kit-Expression in small cell carcinoma of the urinary bladder: prognostic and therapo utic implications[J]. Mod Pathol, 2005, 18(3): 320-323.
15.	程亮, 黃文斌, 陳杰. 膀胱小細胞癌臨床病理學和分子遺傳學研究進展[J]. 中華病理學雜志, 2007, 36(10): 700-702.

1. 　Cramer SF, Aikawa M, Cebelin M. Neurosecretory granules in small cell invasive carcinoma of the urinary bladder[J]. Cancer, 1981, 47(4): 724-30.
2. 　Selli C, Gelmini S, Scott CA, et al. Evidence for elevated telomerase activity in small cell carcinoma of the bladder[J]. Urology, 2000, 56 (2): 331.
3. 　Holmang S, Borghede G, Johansson SL. Primary small cell car- cinoma of the bladder:a report of 25 cases[J]. J Urol, 1995, 153(6): 1820-1822.
4. 　Cheng L, Pan CX, Yang XJ, et al. Small cell carcinoma of the urinary bladder: a clinicopathologic analysis of 64 patients[J]. Cancer, 2004, 101(5): 957-962.
5. 　Abrahams NA, Moran C, Reyes AO, et al. Small cell carcinoma of the bladder: a contemporary clinicopathological study of 51 cases[J]. Histopathology, 2005, 46(1): 57-63.
6. 　曹志彬. 膀胱小細胞癌: 一種罕見的膀胱癌[J]. 國際泌尿系統雜志, 2006, 26(1): 25-28.
7. 　Bastús R, Caballero JM, González G, et al. Small cell carcinoma of the urinary bladder treated with chemotherapy and radiotherapy: resul tsin five cases[J]. Eur Urol, 1999, 35(4): 323-326.
8. 　Grignon DJ, Ro JY, Ayala AG, et al. Small cell car-cinoma of the urinary bladder. A clinicopathologic analysis of 22 cases[J]. Cancer, 1992, 69(2): 527-536.
9. 　潘進勇, 王曉維. 膀胱小細胞癌的研究進展[J]. 中華腫瘤防治雜志, 2007, 6(14): 864-865.
10. 　Abbas F, Civantos F, Benedetto P, et al. Small cell carcinoma of the bladder and prostate[J]. Urology, 1995, 6(5): 617-630.
11. 　Choong NW, Quevedo JF, Kaur JS. Small cell carcinoma of the urinary bladder. The Mayo Clinic experience[J]. Cancer, 2005, 103(6): 1172-1178.
12. 　Dreicer R, Manola J, Roth BJ, et al. Phase Ⅱ study of cisplatin and paclitaxel in advanced carcinoma of the urothelium: an Eastern Cooperative Oncology Group Study[J]. J Clin Oncol, 2000, 18(5): 1058-1061.
13. 　Bajorin DF, McCafrey JA, Dodd PM, et al. Ifosfamide, paclitaxel, and cisplatin for patients witll advanced transitional cell carcinoma of the urothelial tract: final report of a phase Ⅱ trial evaluating two dosing schedules[J]. Cancer, 2000, 88(7): 1671-1678.
14. 　Pan CX, Yang XJ, Lopez-Behran A, et al. c-kit-Expression in small cell carcinoma of the urinary bladder: prognostic and therapo utic implications[J]. Mod Pathol, 2005, 18(3): 320-323.
15. 　程亮, 黃文斌, 陳杰. 膀胱小細胞癌臨床病理學和分子遺傳學研究進展[J]. 中華病理學雜志, 2007, 36(10): 700-702.

《華西醫學》

膀胱小細胞癌一例

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《華西醫學》

膀胱小細胞癌一例

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

Format

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