老年人頸動脈粥樣硬化臨床特點及相關危險因素的研究_《華西醫學》

作者：

四川大學華西醫院老年科,四川成都 610041;

關鍵詞：

頸動脈粥樣硬化老年人頸動脈內中膜厚度頸動脈斑塊

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目的:探討老年人頸動脈粥樣硬化臨床特點及其相關危險因素。方法:收集符合納入標準的住院老年患者臨床資料,頸動脈多普勒檢測頸總動脈內中膜厚度(IMT)、斑塊有無及性質、管腔狹窄程度。結果:(1)老年人群頸總動脈IMT異常者占50.53％;頸動脈斑塊陽性者占78.7％;頸動脈狹窄者占20％,以輕度狹窄為主。(2)頸動脈斑塊好發部位依次是左頸總分叉、左頸總動脈、右頸總動脈、右頸總分叉、頸動脈竇、左頸內動脈、右頸內動脈、右頸外動脈、左頸外動脈。(3)頸動脈斑塊陽性人群合并高血壓心肌梗塞腦血管意外和心腦血管事件率增加。(4)頸動脈IMT異常組較IMT正常組年齡、收縮壓、甘油三酯,合并腦血管事件和心腦血管事件明顯增加,同時頸總動脈IMT增厚伴頸動脈斑塊陽性率、管腔狹窄率及斑塊累及部位增加。結論:老年患者頸動脈粥樣硬化的發病率高,斑塊好發于頸動脈分叉、頸總動脈、頸內動脈,并以左側常見。頸總動脈IMT異常組合并腦血管事件和心腦血管事件率明顯增加,頸總動脈IMT增厚增加頸動脈斑塊和管腔狹窄的發生率。

引用本文： 姜愛俠,丁群芳,羅方,許婷媛,張燕. 老年人頸動脈粥樣硬化臨床特點及相關危險因素的研究. 華西醫學, 2009, 24(4): 881-884. doi: 復制

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2.	EJ LEE, HJ KIM, JM BAE, et al.Relevance of Common Carotid Intima-Media Thickness and Carotid Plaque as Risk Factors for Ischemic Stroke in Patients with Type 2 DiabetesMellitus[J].Am J Neuroradiol,2007,28:916-19..
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4.	RONGLING LI, BRUCE B DUNCAN, PATRICIA A METCALF, et al. B-Mode-Detected Carotid Artery Plaque in a General Population[J].Stroke,1994,25:2377-2383..
5.	ROSFORS S, STEM S H, RERSTIN J U, et al. Relationship between intima- media thickness in the common carotid artery and atherosclerosis in the carotid bifurcation[J].Stroke,1998,29(7):1378-1382..
6.	MARY J ROMAN, TASNEEM Z NAQVI, JULIUS M GARDIN, et al. American Society of Echocardiography Report Clinical application of noninvasive vascular ultrasound in cardiovascular risk stratification:a report from the American Society of Echocardiography and the Society for Vascular Medicine and Biology[J].Vascular Medicine,2006,11:201-211..
7.	ROMAN KOMOROVSKY, ALESSANDRO DESIDERI, et al. Carotid ultrasound assessment of patients with coronary artery disease:a useful index for risk stratification[J].Vascular Health and Risk Management,2005,1(2):131-136..
8.	AKIHIKO KITAMURA, HIROYASU ISO, HIRONORI IMANO, et al. Carotid Intima-Media Thickness and Plaque Characteristics as a Risk Factor for Stroke in Japanese Elderly Men[J].Stroke,2004,35:2788-2794.
9.	JIE J CAO, ALICE, ARNOLD, et al. Association of Carotid Artery Intima-Media Thickness,Plaques,and C-Reactive Protein With Future Cardiovascular Disease and All-Cause Mortality The Cardiovascular Health Study[J].Circulation,2007,116:32-38.
10.	YOSHIHIRO SEO, SHIGEYUKI WATANABE, TOMOKO ISHIZU, et al. Echolucent Carotid Plaques as a Feature in Patients With Acute Coronary Syndrome[J].Circ J,2006,70:1629-1634..
11.	LLOYD E CHAMBLESS, GERARDO HEISS, AARON R FOLSOM. Association of Coronary Heart Disease Incidence with Carotid Arterial Wall Thickness and Major Risk Factors:The Atherosclerosis Risk in Communities(ARIC)Study,1987-1993[J].Am J Epidemiol,1997,146:483-94..
12.	ANNE B NEWMAN, BARBARA L NAYDECK, DIANE G IVES, et al. Coronary Artery Calcium,Carotid Artery Wall Thickness and Cardiovascular Disease Outcomes in Adults 70 to 99 Years Old[J].Am J Cardiol.2008,101(2):186-192.

1. PJ TOUBOUL, MG HENNERICI, S MEAIRS, et al.Mannheim Carotid Intima-Medi Thickness Consensus(2004-2006)[J].Cerebrovasc Dis,2007,23:75-80..
2. EJ LEE, HJ KIM, JM BAE, et al.Relevance of Common Carotid Intima-Media Thickness and Carotid Plaque as Risk Factors for Ischemic Stroke in Patients with Type 2 DiabetesMellitus[J].Am J Neuroradiol,2007,28:916-19..
3. PATRICK J DEVINE, DANIEL W CARLSON, et al. Clinical value of carotid intima-media thickness testing[J].J Nucl Cardiol,2006,13:710-8..
4. RONGLING LI, BRUCE B DUNCAN, PATRICIA A METCALF, et al. B-Mode-Detected Carotid Artery Plaque in a General Population[J].Stroke,1994,25:2377-2383..
5. ROSFORS S, STEM S H, RERSTIN J U, et al. Relationship between intima- media thickness in the common carotid artery and atherosclerosis in the carotid bifurcation[J].Stroke,1998,29(7):1378-1382..
6. MARY J ROMAN, TASNEEM Z NAQVI, JULIUS M GARDIN, et al. American Society of Echocardiography Report Clinical application of noninvasive vascular ultrasound in cardiovascular risk stratification:a report from the American Society of Echocardiography and the Society for Vascular Medicine and Biology[J].Vascular Medicine,2006,11:201-211..
7. ROMAN KOMOROVSKY, ALESSANDRO DESIDERI, et al. Carotid ultrasound assessment of patients with coronary artery disease:a useful index for risk stratification[J].Vascular Health and Risk Management,2005,1(2):131-136..
8. AKIHIKO KITAMURA, HIROYASU ISO, HIRONORI IMANO, et al. Carotid Intima-Media Thickness and Plaque Characteristics as a Risk Factor for Stroke in Japanese Elderly Men[J].Stroke,2004,35:2788-2794.
9. JIE J CAO, ALICE, ARNOLD, et al. Association of Carotid Artery Intima-Media Thickness,Plaques,and C-Reactive Protein With Future Cardiovascular Disease and All-Cause Mortality The Cardiovascular Health Study[J].Circulation,2007,116:32-38.
10. YOSHIHIRO SEO, SHIGEYUKI WATANABE, TOMOKO ISHIZU, et al. Echolucent Carotid Plaques as a Feature in Patients With Acute Coronary Syndrome[J].Circ J,2006,70:1629-1634..
11. LLOYD E CHAMBLESS, GERARDO HEISS, AARON R FOLSOM. Association of Coronary Heart Disease Incidence with Carotid Arterial Wall Thickness and Major Risk Factors:The Atherosclerosis Risk in Communities(ARIC)Study,1987-1993[J].Am J Epidemiol,1997,146:483-94..
12. ANNE B NEWMAN, BARBARA L NAYDECK, DIANE G IVES, et al. Coronary Artery Calcium,Carotid Artery Wall Thickness and Cardiovascular Disease Outcomes in Adults 70 to 99 Years Old[J].Am J Cardiol.2008,101(2):186-192.

《華西醫學》

老年人頸動脈粥樣硬化臨床特點及相關危險因素的研究

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《華西醫學》

老年人頸動脈粥樣硬化臨床特點及相關危險因素的研究

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

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Content

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